epicite® BALANCE

Hydroactive wound dressings for chronic and complex wounds

epicite® BALANCE: HYDRO-ACTIVE WOUND DRESSINGS
FOR EFFECTIVE TREATMENT OF CHRONIC & SLOW-HEALING WOUNDS

epicite® BALANCE is an advanced wound dressing for the treatment of chronic and complex wounds. The dressing is made from a unique, nature-identical material: biosynthetic cellulose. The fine fiber network of biosynthetic cellulose creates an ideal moist wound environment, while absorbing up to 35%* more exudate than comparable products that are applied to the wound in a dry state. The external moisturization provided by epicite® BALANCE supports wound bed preparation and stimulates autolytic debridement, thereby reactivating healing.

epicite® BALANCE is produced in Germany using a fermentative process and renewable resources by JeNaCell - An Evonik company.

* Zahel P et al. (2022). Bacterial Cellulose – Adaptation of a Nature-Identical Material to the Needs of Advanced Chronic Wound Care. Pharmaceuticals 2022;15;683. DOI: 10.3390/ph15060683.

ADVANTAGES OF EPICITE® BALANCE WOUND DRESSINGS MADE FROM BIOSYNTHETIC CELLULOSE

Flexibly adjustable

Material can be cut to fit, it is easy to tamponade and is suitable for deep and fissured wounds.

Moisture donating

Removes plaque and stimulates autolytic debridement

Natural

Biosynthetic cellulose is a well-tolerated material

Time- and cost-effective

Low-pain dressing change and removal in one piece without leaving any residue; enables longer rest phases

OUR PRODUCTS

epicite® BALANCE is available in three practical sizes, allowing flexible use depending on the wound area and treatment requirements. Each size is supplied in packs of ten, ensuring efficient handling and consistent quality.

 

epicite® BALANCE
4cm X 6cm
10 Pcs
Item no.: 18494830

epicite® BALANCE
10cm X 10cm
10 Pcs
Item no.: 18494847

epicite® BALANCE
15cm X 20cm
10 Pcs
Item no.: 18494876

APPLICATION AREAS
OF EPICITE® BALANCE

epicite® BALANCE can be used to treat chronic wounds with low to moderate exudate levels, such as:

  • Venous leg ulcers
  • Ulcus cruris venosum
  • Ulcus cruris mixtum
  • Diabetic foot ulcers
  • Pressure ulcers
  • Soft tissue lesions

The flexible, skin-friendly wound dressing allows for low-pain dressing changes without leaving any residue in the wound. epicite® BALANCE is typically changed after 2 to 7 days, depending on the amount of exudate and the microbial load.

epicite® BALANCE consists of a matrix of biosynthetic cellulose and more than 95% saline solution.

HOW IT WORKS: IMPROVED WOUND HEALING WITH EPICITE® BALANCE

Biosynthetic cellulose is a nature-identical, skin-friendly material with many benefits:

  • Supports wound bed preparation
  • Effectively removes slough, plaque and devitalized tissue
  • Reactivates healing of chronic and complex wounds
  • Re-balances a moist wound environment
  • Simultaneously absorbs wound exudate

Direct contact with the wound bed and covering with secondary dressing

BIOSYNTHETIC CELLULOSE –
A UNIQUE WOUND DRESSING MATERIAL

A – Product Image

B – Scanning Electron Microscopy (SEM)
1K Magnification

B – Scanning Electron Microscopy (SEM)
10K Magnification

C – Illustration

The Biosynthetic Cellulose wound dressing epicite® BALANCE (A) is composed of an ultra-fine, homogenous, three-dimensional cellulose fiber network, as shown through 1K and 10K magnifications (B). This structure creates a high surface area-to-volume ratio.

The cellulose fibers are highly hydrophilic, meaning they attract and bind water molecules (C, depicted as blue dots). This ensures that the spaces between the fibers are filled with water.

The combination of the fine fiber network and its water-attracting properties enables the material to store large amounts of water, making it ideal for maintaining a moist wound environment and promoting optimal healing conditions.

APPLICATION

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CASE REPORTS WITH EPICITE® BALANCE

Case report 1: Venous leg ulcer in post-thrombotic syndrome

A 45-year-old male patient presented to a specialized wound care center with a longstanding venous leg ulcer on his left leg following a deep vein thrombosis. He underwent placement of an inferior vena cava filter and was receiving NOACs, as well as antiretroviral HIV triple therapy.

Wound condition

  • Venous leg ulcer following deep vein thrombosis
  • Dry, scaly ulcer with intense hemosiderin-induced discoloration, fibrous tissue, and no exudation at the start of the observation period

Wound care

  • Primary dressing: epicite®
  • Secondary dressing: gauze bandages, later replaced by film dressing
  • Adjunctive therapy: compression therapy
  • Dressing change intervals: 2/week

Wound healing

  • Significant improvement within 3 weeks, with near-complete closure of the ulcer
  • Complete wound closure after 4 weeks, with softened peri-wound skin

Conclusion

  • Wound responded favorably to epicite® dressing despite the patient's complex medical condition
  • Moist environment created by epicite® likely facilitated the healing process, softening the hard, scaly tissue and supporting wound closure
Case report 2: Pressure ulcer stage IV

A 67-year-old male patient with advanced Parkinson's disease, dementia, and type 2 diabetes mellitus presented with a stage IV pressure ulcer at the sacrum in a severely reduced general condition. Due to the refusal of surgical debridement and hospitalization, palliative co-management was sought. The patient exhibited fever, apathy, and cachexia, accompanied by renal insufficiency and complete immobility.

Wound condition

  • Stage IV pressure ulcer
  • Pronounced necrotic tissue
  • Noticeable odor and heavy exudation

Wound care

  • Primary dressing: epicite®
  • Secondary dressing: absorbent compress
  • Adjunctive therapy: alternating pressure system, wound disinfection with octenidine, later hypochlorite wound irrigation solution
  • Dressing change intervals: daily

Wound healing

  • Effective softening and subsequent dissolution of necrotic tissue by epicite®
  • Reactivation of wound healing, followed by complete wound closure

Conclusion

  • Effective wound cleansing and odor control by epicite®
  • Positive healing progression to complete wound closure despite palliative care approach
Case report 3: Pretibial, arterial ulceration with exposed tendon

A 95-year-old female with a complex medical history including postinterventional peripheral arterial occlusive disease and heart failure presented with a pretibial ulceration, necessitating a tailored approach to wound care.

Wound condition

  • Pretibial ulceration on the right leg with exposed tibialis anterior tendon
  • Partially fibrinoid-necrotic tissue at the distal pole
  • Moderate exudation with no signs of inflammation

Wound care

  • Primary dressing: epicite®, loaded with polyhexanide, later hypochlorite-based solution
  • Secondary dressing: film dressing
  • Dressing change intervals: 2/week

Wound healing

  • Granulation tissue formation observed by day 4
  • Complete resolution of coatings and near-complete overgranulation of the tendon by day 8
  • No drying-out of the tendon observed
  • Antimicrobial treatment with hypochlorite-based solution initiated at day 8 due to signs of infection and inflammation

Conclusion

  • Effective and prolonged hydration of the tendon by epicite® led to rapid formation of new granulation tissue

To see all the details of the case reports get the download

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