Hydro Active

Wound Dressing

Hydroactive Wound Dressing

epicite^® balance

epicite^® balance is an advanced wound dressing for the treatment of chronic and complex wounds. The dressing is made from a unique, nature-identical material: biosynthetic cellulose. The fine fiber network of biosynthetic cellulose creates an ideal moist wound environment, while absorbing up to 35%* more exudate than comparable products that are applied to the wound in a dry state. The external moisturization provided by epicite^® balance supports wound bed preparation and stimulates autolytic debridement, thereby reactivating healing.

epicite^® balance is produced in Germany using a fermentative process and renewable resources by JeNaCell - An Evonik company.

* Zahel P et al. (2022). Bacterial Cellulose – Adaptation of a Nature-Identical Material to the Needs of Advanced Chronic Wound Care. Pharmaceuticals 2022;15;683. DOI: 10.3390/ph15060683.

Improved wound healing with epicite^® balance

Biosynthetic cellulose is a nature-identical, skin-friendly material with many benefits:

Supports wound bed preparation
Effectively removes slough, plaque and devitalized tissue
Reactivates healing of chronic and complex wounds
Re-balances a moist wound environment
Simultaneously absorbs wound exudate

Direct contact with the wound bed and covering with secondary dressing

Flexibly adjustable

Material can be cut to fit, it is easy to tamponade and is suitable for deep and fissured wounds.

Moisture donating

Removes plaque and stimulates autolytic debridement

Natural

Biosynthetic cellulose is a well-tolerated material

Time- and cost-effective

Low-pain dressing change and removal in one piece without leaving any residue; enables longer rest phases

Application of epicite^® balance

epicite^® balance can be used to treat chronic wounds with low to moderate exudate levels, such as:

Venous leg ulcers
Ulcus cruris venosum
Ulcus cruris mixtum
Diabetic foot ulcers
Pressure ulcers
Soft tissue lesions

The flexible, skin-friendly wound dressing allows for low-pain dressing changes without leaving any residue in the wound. epicite® balance is typically changed after 2 to 7 days, depending on the amount of exudate and the microbial load.

epicite^® balance consists of a matrix of biosynthetic cellulose and more than 95% saline solution.

Frequently asked questions

Read our practical guide before using epicite® balance for the first time or if you have any questions. We have summarised your questions and the answers to them here.

Download FAQ here

Case reports

To see all the details of the case reports, please log in here as a healthcare professional.

Case Report Venous leg ulcer in post-thrombotic syndrome

This 45-year-old male patient presented to a specialized wound care center with a longstanding venous leg ulcer on his left leg following a deep vein thrombosis. He underwent placement of an inferior vena cava filter and was receiving NOACs, as well as antiretroviral HIV triple therapy.

Wound condition

Venous leg ulcer following deep vein thrombosis
Dry, scaly ulcer with intense hemosiderin-induced discoloration, fibrous tissue, and no exudation at the start of the observation period

Wound care

Primary dressing: epicite®
Secondary dressing: gauze bandages, later replaced by film dressing
Adjunctive therapy: compression therapy
Dressing change intervals: 2/week

Wound healing

Significant improvement within 3 weeks, with near-complete closure of the ulcer
Complete wound closure after 4 weeks, with softened peri-wound skin

Conclusion

Wound responded favorably to epicite® dressing despite the patient's complex medical condition
Moist environment created by epicite® likely facilitated the healing process, softening the hard, scaly tissue and supporting wound closure

Case Report Pressure ulcer stage IV

A 67-year-old male patient with advanced Parkinson's disease, dementia, and type 2 diabetes mellitus presented with a stage IV pressure ulcer at the sacrum in a severely reduced general condition. Due to the refusal of surgical debridement and hospitalization, palliative co-management was sought. The patient exhibited fever, apathy, and cachexia, accompanied by renal insufficiency and complete immobility.

Wound condition

Stage IV pressure ulcer
Pronounced necrotic tissue
Noticeable odor and heavy exudation

Wound care

Primary dressing: epicite®
Secondary dressing: absorbent compress
Adjunctive therapy: alternating pressure system, wound disinfection with octenidine, later hypochlorite wound irrigation solution
Dressing change intervals: daily

Wound healing

Effective softening and subsequent dissolution of necrotic tissue by epicite®
Reactivation of wound healing, followed by complete wound closure

Conclusion

Effective wound cleansing and odor control by epicite®
Positive healing progression to complete wound closure despite palliative care approach

Case Report Pretibial, arterial ulceration with exposed tendon

A 95-year-old female with a complex medical history including postinterventional peripheral arterial occlusive disease and heart failure presented with a pretibial ulceration, necessitating a tailored approach to wound care.

Wound condition

Pretibial ulceration on the right leg with exposed tibialis anterior tendon
Partially fibrinoid-necrotic tissue at the distal pole
Moderate exudation with no signs of inflammation

Wound care

Primary dressing: epicite®, loaded with polyhexanide, later hypochlorite-based solution
Secondary dressing: film dressing
Dressing change intervals: 2/week

Wound healing

Granulation tissue formation observed by day 4
Complete resolution of coatings and near-complete overgranulation of the tendon by day 8
No drying-out of the tendon observed
Antimicrobial treatment with hypochlorite-based solution initiated at day 8 due to signs of infection and inflammation

Conclusion

Effective and prolonged hydration of the tendon by epicite® led to rapid formation of new granulation tissue

Product information

Sterile, individually packed

Product	Size in cm	Pcs./Package	PZN
epicite^® balance	4x6	10	18494830
epicite^® balance	10x10	10	18494847
epicite^® balance	15x20	10	18494876

epicite^® balance 4 cm x 6 cm, PZN: 18494830

epicite^® balance 10 cm x 10 cm, PZN: 18494847

epicite^® balance 15 cm x 20 cm, PZN: 18494876

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Join us at upcoming trade shows and conferences

Date	Event
March 26 – 28, 2025	EWMA (European Wound Management Association), Barcelona
April 16, 2025	1. Sächsischer Wundkongress
May 7 – 9, 2025	DEWU Bremen
September 25 – 26, 2025	Wundkosmos Berlin
November 27, 2025	Interdisziplinärer WundCongress Köln
December 4 – 5, 2025	Nürnberger Wundkongress

Hydroactive Wound Dressing

epicite^® balance